Corneal response to rigid contact lens wear.

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Corneal response to rigid contact lens wear.

Three adult rhesus monkeys were subjected to 2 and 24 hours of polymethylmethacrylate (PMMA) contact lens wear. The induced corneal changes were examined with the electron microscope. Mild epithelial oedema as well as early degenerative cell changes was present already after 2 hours' wear. Rigid lens wear for 24 hours produced more severe oedema and cell alterations together with premature cell...

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Proliferation rate of rabbit corneal epithelium during overnight rigid contact lens wear.

PURPOSE To examine cell proliferation of the normal corneal epithelium and during extended rigid gas-permeable (RGP) lens wear. METHODS Twenty-three New Zealand White rabbits were fitted unilaterally with either a low oxygen transmissible (Dk/t) or hyper-Dk/t RGP lens, with the other eye serving as a control. The rabbits were injected with 5-bromo-2-deoxyuridine (BrdU) 24-hours later and kill...

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Impact of rigid gas-permeable contact lens extended wear on corneal epithelial barrier function.

PURPOSE To measure the effect of hypoxia and eye closure on epithelial permeability to fluorescein (P(dc)) during rigid lens extended wear (EW). METHODS Central corneal thickness (CT) and P(dc) were measured in 42 subjects with an optical pachometer and automated scanning fluorophotometer, respectively. All subjects had been successfully wearing rigid gas-permeable (RGP) lenses on a 6-night E...

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Corneal aberration changes after rigid gas permeable contact lens wear in keratokonic patients

PURPOSE To determine the short-term effect of rigid gas permeable (RGP) contact lenses on corneal aberrations in keratoconic patients. METHOD Sixteen keratoconic eyes with no history of RGP lens wear were included. They all had corneal aberrometry using Pentacam, and different aberration indices of the anterior and posterior surfaces of the cornea were measured before and 3 months after fitti...

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Corneal oxygenation: blink frequency as a variable in rigid contact lens wear.

Using a micropolarographic system, we measured the responses of six human corneas to nine oxygen exposure conditions: to air (continuous open-eye) with no contact lens in place, and to eight interblink intervals (1, 2, 3, 4, 5, 6, 7, and 300 s durations) with an oxygen impermeable lens in place. The corneal oxygen uptake rates immediately following each of those conditions were direct indices o...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1982

ISSN: 0007-1161

DOI: 10.1136/bjo.66.10.667